This
page discusses sex hormone deficiency, health risks, effects of hormone
deficiency, body and tissue effects of hormonal deficiency...
WHAT ARE
THE EFFECTS OF HORMONE DEFICIENCY?
Hormone deficiency
affects all parts of the body, and so, all tissues dependent on the
hormone are compromised. When the duration of hormone loss is prolonged
or acute, as is the case of a premature menopause or removal of the
ovaries, the effect is magnified. Hormonally dependent tissues cannot
and do not function optimally or maintain their integrity when the required
hormone is absent.
Hormone deficiency
causes an increase in the incidence of coronary artery disease, strokes,
osteoporosis and possibly Alzheimer's disease. Fortunately the increase
in frequency of these problems can be prevented by appropriate use of
HRT.
DOES THAT
MEAN I WILL DEFINITELY HAVE PROBLEMS IF I DON'T TAKE HRT?
It is impossible
to predict if a specific woman will experience problems, however there
are a number of factors that significantly increase the risk:
•Heredity: A family history of Osteoporosis, Cardiovascular Disease
or Alzheimer's.
•Surgical removal of the ovaries: Unlike a natural menopause where
the fall is more gradual, the decline in ovarian sex hormone production
is sudden and complete and so women in this category tend to be at greater
risk.
•Early menopause: Early menopause can be due to premature menopause,
surgery or ovarian injury. The risks begin once the hormone levels decrease,
and the they increases with each passing month that the problem is not
corrected..
•Lifestyle: Smoking, excess alcohol intake, sedentary lifestyle,
high fat diet and low intake of calcium and other important nutrients
all affect the risk factor.
•Concurrent medical problems: There are a number of medical conditions
that increase risk, either as an effect of the disease itself or the
medication necessary to treat it.
WHAT TYPES
OF MEDICAL PROBLEMS INCREASE RISK?
Here are a few examples.
Elevated levels of lipids (fats) in the blood, hypertension, obesity
and diabetes increase the risk of coronary artery disease and stroke.
There are also a
number of medical conditions that risk of osteoporosis including diseases
of kidney function and calcium metabolism, of stomach and intestinal
absorption, chronic lung disease, hyperthyroidism and Cushings disease
- a disorder of the adrenal gland.
Medications can
also cause problems. Medications called glucocorticoids, such as prednisone
given in high doses over a period of time as short as a few months can
cause significant mineral loss from bone as can heparin an anticoagulant.
Also, thyroid hormone in excess of replacement requirements taken over
an extended period of time results in significant bone loss as well.
WILL MENOPAUSE
CHANGE THE WAY I FEEL?
The majority of
women experience symptoms which range from mild to debilitating, including
hot flushes, sweats, insomnia, problems with memory and/or concentration,
headaches, loss of sex drive, mood changes, and muscle aches. A woman
may experience some of these symptoms, all of them, or none of them.
WILL MENOPAUSE
CHANGE MY BODY?
Almost all women
will experience alterations in sex hormone dependent "target tissues"
and "organ systems". This includes atrophy of the vagina,
urethra, labia and clitoris, loss of skin thickness and collagen content,
loss of bone mineral content from the skeleton as well as effects on
the brain and cardiovascular system. Again, these changes are preventable
by appropriate use of HRT.
WHAT HAPPENED
TO THAT "YOU'RE NOT GETTING OLDER, YOU'RE GETTING BETTER"
STUFF?
I know Aunt Sadie
lived to 94, was sharp as a tack, had a younger boyfriend she nearly
killed with her sexual demands, drove a car, mowed her lawn and was
active until the day she died. Everybody thinks it's great. Hormonally
deficient people can function, of course they can. Aunt Sadie did. But
that's not issue. The point is that no one, regardless of gender can
function optimally, if they are hormonally deficient.