What is
Migraine?
Migraine is an inherited,
or acquired combined disorder of the nerve and vascular tissue of the
brain. The manifestation of this disorder is the headache, which occurs
intermittently as a result of a stimulus or "trigger." In
those affected, the frequency can vary markedly, and the headaches can
occur rarely or on a daily basis. Common triggers include, odors, flashing
lights, stress, lack of sleep and other various stimuli. Hormones can
act as a trigger and a common variety of this is what is called "menstrual
headache." This type of migraine is usually related to the fall
in estrogen levels that occurs prior to menstruation. It is also likely
that progesterone sensitivity plays a role as well in many women.
I have recently
become menopausal and I am having trouble with migraine headaches. Why?
If migraine headaches
occur initially, or become significantly worse following menopause,
especially a surgical one, the possibility that it is related to your
menopause and its associated hormonal alterations is certainly a reasonable
consideration.
Is this
because of my hormone replacement therapy / HRT?
When migraine occurs
in post menopausal women there a number possibilities that can be considered.
Migraine usually
does not occur as a result of estrogen itself, but rather changes in
estrogen levels. The fall in estrogen levels that occurs at menopause
can trigger migraine. This is particularly true when the menopause is
surgical and the fall in hormone levels is abrupt. Regimens in which
the estrogen levels vary widely, such as estrogen injections given on
a monthly basis can potentially trigger migraine as the estrogen levels
are very high immediately following the injection and fall off rapidly.
In some instances
women who take oral estrogen preparations suffer from migraine triggered
by substances produced as a byproduct of the inherent "first pass
liver metabolism" of oral estrogen.
If the woman has
a uterus and the headaches occur during the time she is taking the progesterone
component of her hormone replacement therapy regimen, one would expect
that they are due to either the progesterone, which has anti estrogenic
affects, and/or falling estrogen levels if her regimen includes stopping
her estrogen prior to her withdrawal bleeding.
What to
do?
The first thing
to do would be to see a neurologist to make sure that the headaches
are not due to another problem. The neurologist can also discuss whether
it would be better to treat the individual headaches if they do not
occur too frequently, or to prescribe preventative therapy if they do.
Should I
change my hormone replacement therapy / HRT regimen?
It would make sense
to use a non oral regimen of hormone replacement therapy, preferably
one that results in consistent hormone levels. Ideally, this would be
an estrogen patch or gel, or subcutaneous hormone implants. Some menopausologists
feel that migraine can occur as a result of testosterone deficiency
especially when there has been a surgical removal of the ovaries and
have had some success by replacing testosterone levels along with estrogen.
Physicians who use subcutaneous hormone implants may be particularly
successful when this is the problem. They are able to replace the estrogen
and testosterone in a manner where after the initial rise in hormone
levels occur, the day to day change in hormone levels is fairly small.
I had some success using this method in selected patients, however the
headaches returned when the hormone levels dropped below a critical
point which was unique to each individual. At that time, ideally, implantation
of hormones would be repeated. Testosterone patches in appropriate doses
for women are not made in the United States, and so one of the available
male replacement patches would have to be cut to an appropriate dosage
size or a testosterone gel would have to be obtained from a compounding
pharmacy. In either case, blood could be drawn to monitor levels to
ascertain that the levels are in the desired range.
Menopause
Overview
This page defines and discusses menopause, surgical menopause and
premature menopause...
Menopausal
Symptoms
A woman may experience a number of changes in the way she feels at or
prior to menopause. We call these changes the "symptoms" of
menopause. This page defines and discusses menopausal symptoms and their
treatment...
Sex
and Menopause
Loss of sexual desire and ability to participate in and enjoy sex is
not a normal part of aging. Dr Nosanchuk explains why a menopausal woman's
desire to have sex and her capacity to physically participate in sex
are both affected by her menopause...
Menopause
& Weight Gain
Dr Nosanchuk discusses the factors that influence weight gain in
menopausal women...
Menopause & Hair Loss
One of the concerns shared by women of menopausal age is the possibility
of hair loss. The importance modern society associates with an attractively
styled hairdo is reflected by a thriving multi-billion dollar industry
involved in the cutting, styling, washing and coloring of hair. When
hair loss occurs to a menopausal woman, it is certainly stressful, as
this situation may diminish body image satisfaction and self-esteem.
The impact can be devastating and affect psychological adjustment and
quality of life ...