Hot
Flashes, Sweats, Heat Intolerance and Chills:
The hot flash or the more descriptive term the hot flush is the symptom
commonly associated with menopause. Many people are under the impression
that hot flushes are the only significant manifestation of menopause,
other than the cessation of regular menstrual cycles. When you here someone
say, "I’ve gone through menopause", or "I can’t
wait until I’m done with menopause", it is likely that they
equate no longer having flushes as a sign that they have "gone through"
menopause. However, no one "goes through" menopause. Once you
become hormonally deficient you remain so for the rest of your life.
About 75% of women
experience hot flushes, heat intolerance or sweats sometime during or
prior to their menopause. Although these symptoms resolve within two
years in most of those affected, they may last five years or more in
approximately 20% of women. I have had patients in their 80’s
in whom these symptoms persisted. Some patients experience chills in
a similar fashion to the hot flush and it is likely a variant of the
same phenomenon.
The hot flush can
range from a barely perceptible feeling of warmth to intense heat of
the chest, neck and head and can be accompanied by profuse flushing
and sweats. Many women develop chronic heat intolerance in lieu of or
in addition to flushing. They will often wear light clothing in the
middle of the winter and prefer to set the thermostat in their homes
at a level that is noticeably cool for the rest of their family. One
patient told me that in the middle of the winter she would stand in
her unheated garage several times a day as it was the only place she
could find at least temporary relief for her discomfort. These patients
are very uncomfortable in warm weather and many have told me that vacationing
in a tropical climate was out of the question for them.
Mild flushing episodes
can often be ignored but as they progress in intensity they can become
annoying, distracting, embarrassing and in the worst case scenarios
debilitating. Menopausal women often know when the flush is about to
begin before they are aware of any sense of heat or flushing. Usually,
women who have undergone ovarian removal experience the most severe
symptoms and there may be associated nausea, urinary urgency or an impending
sense of doom. The flushes can last from several seconds to as long
as thirty minutes and sometimes as long as an hour and can occur from
rarely to every ten to thirty minutes. They tend to be more frequent
and severe during the night and often disturb sleep. Associated sweats
may be so severe as to necessitate a change of sleepwear.
Women experiencing
severe flushes may be unable to work and have difficulty performing
the routine activities of daily living. A menopausal woman who is delivering
a business presentation and has a severe flushing episode may find it
difficult if not impossible to continue. Stressful situations, warm
temperatures, alcohol, hot food, warm clothing and exercise are frequently
precipitating factors. A menopausal woman’s difficulty with flushes
tends to be taken lightly by those never having experienced the symptom,
including other women. One will sometimes hear the phrase, "get
over it", spoken by people insensitive to how disturbing and unpleasant
a flushing episode can be.
There is a story
which appeared in a national news magazine a few years ago written by
a woman who had recently become menopausal. In the article she describes
how she felt during a flushing episode on a cold winter day while walking
in a large northeastern city. Despite the cool weather and her open
coat she was in considerable discomfort. Sweating profusely, she thought,
"I’m sorry mom!", as she remembered how years before
she had lightly dismissed her mother’s readily apparent distress
with similar flushes. The woman was remorseful for her failure to have
been more supportive. Hot flushes, often the butt of jokes about menopause,
may not be amusing to a menopausal woman whose quality of life is affected
by them.
What causes
hot flushes, sweats and heat intolerance?
These symptoms occur
as a response to changing hormone levels which induce confusion (doctors
refer to this as "vasomotor instability") in the temperature
regulating mechanism of the body. Your body "thermostat",
located in an area of the brain called the hypothalamus", is intermittently
fooled into believing that your body temperature should be lower. To
accomplish this the "thermostat" sends signals that cause
warm blood located in the core of your body to be brought to dilated
blood vessels in the surface of your skin where it can be cooled by
the surrounding air. The "sweats" some women experience is
a more extreme cooling measure. Evaporation of liquid in the form of
perspiration from the skin is utilized to reduce body temperature. If
you recall how chilled you feel when you get out of a swimming pool
or a bath, you can see how effective evaporation is as a cooling mechanism.
Is there
a treatment for hot flashes, sweats and heat intolerance?
Hormone replacement
therapy, using estrogen and if needed testosterone, is the most effective
treatment. All the regimens of HRT in routine usage today will relieve
the majority of menopausal women of these symptoms. Whichever regimen
is used, must be taken on a regularly basis for as long as a month to
resolve symptoms. If a program does not prove to be effective, a slightly
higher dose of the same preparation can be tried and if this is not
successful one of the other routes of administration should be given
a trial. I have found that changing preparations that are administered
using the same route of administration is not as effective in relieving
resistant symptoms as changing to a preparation that utilizes an alternate
route of administration.
The treatment program
that is almost always successful even if symptoms have been longstanding
and resistant to other methods of hormone replacement is subcutaneous
implantation of the appropriate dose of estradiol and, if indicated,
testosterone. I have seen patients who had symptoms for as long as thirty
years or more in spite of various types of HRT treatment, whose symptoms
resolved with this route of administration. One of these patients was
in her early 80’s and had experienced flushes and sweats from
the time of her hysterectomy around age 40. Another told me that until
she had the subcutaneous implantation she had slept in a chair for over
20 years, as she was too uncomfortable sleeping in a bed.
Although not as
effective, patients who cannot or prefer not to take estrogen may be
treated with progesterone. Historically Provera, (medroxyprogesterone
acetate) and Megace, (megestrol acetate) have been used for this purpose.
For a more
in depth information about hormone replacement therapy, look at the
About Hormone Replacement Therapy, Methods of Hrt and Regimens sections
of the web site.
Some women are more
comfortable with treatments they are able to obtain themselves without
a prescription at a drug store, health food store, or from a herbalist.
These therapies are sometimes used as complementary therapies along
with prescription treatments. Non prescription therapies are advertised
widely and are available at the local pharmacy. One of the most popular
is vitamin E taken in a dosage of up to 400 IU daily. Natural and alternative
therapies include foods containing plant estrogens called phytoestrogens
and herbal remedies. Soy is an excellent source of phytoestrogen and
a daily intake of soy products may be helpful. Herbal remedies that
are reputed to have estrogenic activity include Dong quai, Ginseng,
and Gotu kola. Unfortunately, there has not been enough research in
this area and much needs to be done to establish proper dosage, safety
and efficacy. Although some women may find that some of their symptoms
are alleviated by these therapies, there is no evidence at present that
they prevent long-term consequences of lowered hormone levels.
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Menopause & Hair Loss
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